BrainXell dedicates over half of its production capacity to custom differentiation services, creating neural and glial cells from hundreds of unique iPSC lines provided by our clients and collaborators. Projects are flexible, accommodating varying scales (from 25 million to 20 billion cells), characterization needs, and delivery formats.
We offer comprehensive support in project design, including iPSC line selection/sourcing, and have extensive experience with disease, isogenic corrected, gene-edited/knockout, and reporter lines. Additionally, we offer control lines for parallel differentiation or third-party gene editing prior to differentiation. As a part of the Edit Co (Synthego) Discovery Partnership Ecosystem, BrainXell control iPSC lines are fast tracked for rapid turnaround of iPSC editing projects.
For virtual companies seeking our services, we can store your cells at our facility and ship them as needed. Alternatively, let our expert scientists establish the highest quality cultures for use in our available in-house assays (see Assay Services).
Custom Differentiation Service Options
| Cell Types Made | Scale | Starting Cells |
| Spinal Motor Neurons
Cortical Glutamatergic Neurons Cortical GABAergic Neurons Spinal Astrocytes Midbrain Dopaminergic Neurons Cortical Astrocytes Microglia |
Minimum 25 million for neurons
Minimum 10 million for astrocytes and microglia Up to 20 billion |
Human iPSCs
Human ESCs Primate iPSCs Primate ESCs Human Fibroblasts
|
Example Project Timeline
Development projects for novel CNS cell types are possible and will be considered on a case-by-case basis. We can perform a feasibility assessment based on our experience and a literature review before proposing a pilot project.
Please contact us to discuss a potential project. Regardless of whether you know exactly what you need or only have a rough idea, we’re happy to see how we can help.