Disease Cells

BrainXell offers a comprehensive range of disease cell products meticulously engineered to advance research in neurodegenerative disorders. Our disease cell models, derived from induced pluripotent stem cells (iPSCs), accurately recapitulate the cellular pathophysiology of various neurological conditions, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). These disease-specific cell lines provide researchers with valuable tools for studying disease mechanisms, screening potential therapeutics, and developing personalized treatment strategies.

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The majority of BrainXell’s items and sizes are available for immediate shipment. Please inquire regarding your order to confirm the current inventory.

Various sizes available; see table below

Microglia with Disease edits

Edits: APOE E3/E3 to APOE E4/E4; TREM2 WT to TREM2 KO or R47H SNP

Isogenic Control Cells Available

Markers: >85% IBA1+, >85% PU.1+

Catalog Number	Cell Type	IPSC Line	Sex	Edit	To Order	hf:categories	hf:att:pa_ipsc-line	hf:att:pa_sex	hf:att:pa_edit
BX-0314-30	Cortical Glutamatergic Neurons	WC-30	M	APOE4/E4	Select options	cortical-glutamatergic-neurons disease-cells neurons	wc-30	m	apoe4-e4
BX-0314-32	Cortical Glutamatergic Neurons	WC-32	F	APOE4/E4	Select options	cortical-glutamatergic-neurons disease-cells neurons	wc-32	f	apoe4-e4
BX-0614-32	Cortical Astrocytes	WC-32	F	APOE4/E4	Select options	cortical-astrocytes disease-cells astrocytes	wc-32	f	apoe4-e4
BX-06514-32	Spinal Astrocytes	WC-32	F	APOE4/E4	Select options	spinal-astrocytes disease-cells astrocytes	wc-32	f	apoe4-e4
BX-0914-32	Microglia	WC-32	F	APOE4/E4	Select options	microglia disease-cells	wc-32	f	apoe4-e4
BX-0920-32	Microglia	WC-32	F	TREM2 KO	Select options	microglia disease-cells	wc-32	f	trem2-ko
BX-0921-32	Microglia	WC-32	F	TREM2 R47H	Select options	microglia disease-cells	wc-32	f	trem2-r47h
BX-0914-30	Microglia	WC-30	M	APOE4/E4	Select options	microglia disease-cells	wc-30	m	apoe4-e4
BX-0924-32	Microglia	WC-32	F	TREM2-H157Y	Select options	microglia disease-cells	wc-32	f	trem2-h157y
BX-1014-30	Endothelial Cells	WC-30	M	APOE4/E4	Select options	endothelial-cells disease-cells	wc-30	m	apoe4-e4
BX-1014-32	Endothelial Cells	WC-32	F	APOE4/E4	Select options	endothelial-cells disease-cells	wc-32	f	apoe4-e4
BX-1614-30	Cortical Astrocytes	WC-30	M	APOE4/E4	Select options	cortical-astrocytes disease-cells astrocytes	wc-30	m	apoe4-e4