Cortical Glutamatergic Neurons

Origin: Human iPSC line

Size: Various sizes available; see table below

Contents: 1 vial of cells and corresponding BrainXell supplements

    GFP-expressing neurons also available
    Cryopreserved

Marker Expression

Cortical Glutamatergic Neurons (BX-0300) have high neuronal purity (>90%) and comprise predominantly excitatory neurons. BrainXell’s human iPSC-derived Cortical Glutamatergic Neurons provide a physiologically relevant model for studying excitatory neurotransmission and neuronal network function in the human cortex. These neurons support research into synaptic signaling, neuronal connectivity, CNS disease mechanisms, and drug discovery, with applications in both monoculture and complex co-culture systems.

Morphology

Cortical Glutamatergic Neurons (BX-0300) exhibit substantial neurite outgrowth within a week in culture and are adherent. Calcein staining (green) demonstrates the characteristic oval cell shape and long processes of Cortical Glutamatergic Neurons in culture.

Function

Cortical Glutamatergic Neurons (BX-0300) exhibit pronounced electrophysiological activity after two weeks in culture, as demonstrated by multi-electrode array (MEA) recordings.

Recommended protocols developed by BrainXell utilize proprietary supplements that are included with each purchase of neurons. The recommended protocol will depend on the application. Contact BrainXell application scientists to learn more.

Discount Pricing for Academics

Request Quote for Large or Custom Orders

The majority of BrainXell’s items and sizes are available for immediate shipment. Please inquire regarding your order to confirm the current inventory.

 BrainXell Co-culture of Neuron_Microglia Protocol v11   BrainXell Cortical Glut Neuron Culture Protocol v10.1   BrainXell Tri-Culture of Neuron_Astrocyte_Microglia Protocol v11   BrainXell Co-Culture of Neuron_Astrocyte Protocol v11.0