Explore BrainXell’s extensive list of publications, covering diverse topics in neuroscience and stem cell biology. Stay informed on the latest research and scientific insights by reading the various publications linked below.

iPSC Sensory Co-Cultures
Umass Lowell

• Phenotypic Screening of Prospective Analgesics Among FDA-Approved Compounds using an iPSC-Based Model of Acute and Chronic Inflammatory Nociception (2024)

BX-0100 Spinal Motor Neurons

University of Pennsylvania

• Motor neurons and endothelial cells additively promote development and fusion of human iPSC-derived skeletal myocytes (2024)

BX-0700 MSNs

Yale

• Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools (2024)

Yale

• Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons (2023)

Cortical Glutamatergic Neurons (BX-0300)
University of Minnesota

• Asher M, McMullan H, Dong AO, Yulong L, Thayer S. (2023) A Complete Endocannabinoid Signaling System Modulates Synaptic Transmission between Human Induced Pluripotent Stem Cell–Derived Neurons. Mol Pharma. Feb, 103 (2) 100-112 (2023)

NETRI

• Tristan Gabriel-Segard, Jessica Rontard, Louise Miny, Louise Dubuisson, Aurélie Batut, Delphine Debis, Mélanie Gleyzes, Fabien François, Florian Larramendy, Alessandra Soriano, Thibault Honegger, and Stéphane Paul. (2023) Proof-of-Concept Human Organ-on-Chip Study: First Step of Platform to Assess Neuro-Immunological Communication Involved in Inflammatory Bowel Diseases. Int. J. Mol. Sci. 2023, 24(13) 

Vivid Microscopy and BrainXell

• Real-time thiol detection in iPSC-derived neuron cultures using SemKur-IM, a novel fluorescent dithio probe (2023)

Spinal Astrocytes (BX-0650)
Umass Lowell

• Lawson J, LaVancher E, DeAlmeida M, Black B. (2023) Electrically-evoked oscillating calcium transients in mono- and co-cultures of iPSC glia and sensory neurons. Front. Cell. Neurosci., vol 17. (2023)

Conditioned media from iPSC-derived neurons
NeuroDex, Alkermes, NIA/NIH, Columbia University

• Eitan E, Thornton-Wells T, Elgart K, Erden E, Gershun E, Levine A, Volpert O, Azadeh M, Smith D, Kapogiannis D. (2023) Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer’s disease: novel methodology and clinical proof of concept. Extracell Vesicles Circ Nucleic Acids 2023;4:133-50 (2023)

Cortical Astrocytes (BX-0600)
Yale

• Kuchroo M, DiStasio M, Song E, Calapkulu E, Zhang L, Ige M, Sheth A, Majdoubi A, Menon M, Tong A, Godavarthi A, Xing Y, Gigante S, Steach H, Huang J, Huguet G, Narain J, You K, Mourgkos G, Dhodapkar R, Hirn M, Rieck B, Wolf G, Krishnaswamy S, Hafler B. (2023) Single-cell analysis reveals inflammatory interactions driving macular degeneration. Nat Commun 14, 2589 (2023)

BX-0100 Spinal motor neurons, BX-0650 spinal astrocytes
Umass Lowell

• Lojek N, Williams V, Rogers A, Sajo E, Black B, Ghezzi C. (2023) A 3D in vitro cortical tissue model based on dense collagen to study the effects of gamma radiation on neuronal function. bioRxiv preprint (2023)

 

BX-0400, Cortical GABA, BX-0600, Cortical Astrocytes, Pfizer lines, SCN1A mutation

Pfizer

• Potentiating NaV1.1 in Dravet syndrome patient iPSC-derived GABAergic neurons increases neuronal
  2 firing frequency and decreases network synchrony (2023)

BX-0400 and BX-0100

Neurona Therapeutics

• Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy